Piecing together nuclear pore complex assembly during interphase

All nucleocytoplasmic traffic of macromolecules occurs through nuclear pore complexes (NPCs), which function as stents in the nuclear envelope to keep nuclear pores open but gated. Three studies in this issue (Flemming, D., P. Sarges, P. Stelter, A. Hellwig, B. Böttcher, and E. Hurt. 2009. J. Cell B...

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Detalles Bibliográficos
Autor principal: Rexach, Michael
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700397/
https://www.ncbi.nlm.nih.gov/pubmed/19414605
http://dx.doi.org/10.1083/jcb.200904022
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author Rexach, Michael
author_facet Rexach, Michael
author_sort Rexach, Michael
collection PubMed
description All nucleocytoplasmic traffic of macromolecules occurs through nuclear pore complexes (NPCs), which function as stents in the nuclear envelope to keep nuclear pores open but gated. Three studies in this issue (Flemming, D., P. Sarges, P. Stelter, A. Hellwig, B. Böttcher, and E. Hurt. 2009. J. Cell Biol. 185:387–395; Makio, T., L.H. Stanton, C.-C. Lin, D.S. Goldfarb, K. Weis, and R.W. Wozniak. 2009. J. Cell Biol. 185:459–491; Onishchenko, E., L.H. Stanton, A.S. Madrid, T. Kieselbach, and K. Weis. 2009. J. Cell Biol. 185:475–491) further our understanding of the NPC assembly process by reporting what happens when the supply lines of key proteins that provide a foundation for building these marvelous supramolecular structures are disrupted.
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spelling pubmed-27003972009-11-04 Piecing together nuclear pore complex assembly during interphase Rexach, Michael J Cell Biol Reviews All nucleocytoplasmic traffic of macromolecules occurs through nuclear pore complexes (NPCs), which function as stents in the nuclear envelope to keep nuclear pores open but gated. Three studies in this issue (Flemming, D., P. Sarges, P. Stelter, A. Hellwig, B. Böttcher, and E. Hurt. 2009. J. Cell Biol. 185:387–395; Makio, T., L.H. Stanton, C.-C. Lin, D.S. Goldfarb, K. Weis, and R.W. Wozniak. 2009. J. Cell Biol. 185:459–491; Onishchenko, E., L.H. Stanton, A.S. Madrid, T. Kieselbach, and K. Weis. 2009. J. Cell Biol. 185:475–491) further our understanding of the NPC assembly process by reporting what happens when the supply lines of key proteins that provide a foundation for building these marvelous supramolecular structures are disrupted. The Rockefeller University Press 2009-05-04 /pmc/articles/PMC2700397/ /pubmed/19414605 http://dx.doi.org/10.1083/jcb.200904022 Text en © 2009 Rexach This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jcb.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
spellingShingle Reviews
Rexach, Michael
Piecing together nuclear pore complex assembly during interphase
title Piecing together nuclear pore complex assembly during interphase
title_full Piecing together nuclear pore complex assembly during interphase
title_fullStr Piecing together nuclear pore complex assembly during interphase
title_full_unstemmed Piecing together nuclear pore complex assembly during interphase
title_short Piecing together nuclear pore complex assembly during interphase
title_sort piecing together nuclear pore complex assembly during interphase
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700397/
https://www.ncbi.nlm.nih.gov/pubmed/19414605
http://dx.doi.org/10.1083/jcb.200904022
work_keys_str_mv AT rexachmichael piecingtogethernuclearporecomplexassemblyduringinterphase

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