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Percutaneous computed tomography-guided core biopsy for the diagnosis of mediastinal masses

AIM: To describe various approaches of computed tomography (CT)-guided core biopsy and evaluate its ability to obtain adequate tissue for the assessment of mediastinal masses. MATERIALS AND METHODS: Between February 2004 and October 2006, 83 percutaneous CT-guided biopsies of mediastinal lesions wer...

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Autores principales: Kulkarni, Suyash, Kulkarni, Aniruddha, Roy, Diptiman, Thakur, Meenakshi H.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700430/
https://www.ncbi.nlm.nih.gov/pubmed/19561877
http://dx.doi.org/10.4103/1817-1737.37948
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author Kulkarni, Suyash
Kulkarni, Aniruddha
Roy, Diptiman
Thakur, Meenakshi H.
author_facet Kulkarni, Suyash
Kulkarni, Aniruddha
Roy, Diptiman
Thakur, Meenakshi H.
author_sort Kulkarni, Suyash
collection PubMed
description AIM: To describe various approaches of computed tomography (CT)-guided core biopsy and evaluate its ability to obtain adequate tissue for the assessment of mediastinal masses. MATERIALS AND METHODS: Between February 2004 and October 2006, 83 percutaneous CT-guided biopsies of mediastinal lesions were performed on 82 patients under local anesthesia. Coaxial needles were used and minimum of 3-4 cores were obtained. Post-biopsy CT scan was performed and patients observed for any complications. Tissue samples were taken to Pathology Department in formalin solution. RESULTS: From the 83 biopsies, adequate tissue for histological diagnosis was obtained in 80 (96%), and the biopsy was considered diagnostic. Of the 80 diagnostic biopsies, 74 biopsy samples were definitive for neoplastic pathology and 6 biopsy samples revealed no evidence of malignancy. There were no major complications. Minor complications were recorded in 5 patients. CONCLUSION: Percutaneous image-guided core biopsy of mediastinal lesions is an accurate, safe and cost-effective tool for the initial assessment of patients with mediastinal masses.
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spelling pubmed-27004302009-06-25 Percutaneous computed tomography-guided core biopsy for the diagnosis of mediastinal masses Kulkarni, Suyash Kulkarni, Aniruddha Roy, Diptiman Thakur, Meenakshi H. Ann Thorac Med Original Article AIM: To describe various approaches of computed tomography (CT)-guided core biopsy and evaluate its ability to obtain adequate tissue for the assessment of mediastinal masses. MATERIALS AND METHODS: Between February 2004 and October 2006, 83 percutaneous CT-guided biopsies of mediastinal lesions were performed on 82 patients under local anesthesia. Coaxial needles were used and minimum of 3-4 cores were obtained. Post-biopsy CT scan was performed and patients observed for any complications. Tissue samples were taken to Pathology Department in formalin solution. RESULTS: From the 83 biopsies, adequate tissue for histological diagnosis was obtained in 80 (96%), and the biopsy was considered diagnostic. Of the 80 diagnostic biopsies, 74 biopsy samples were definitive for neoplastic pathology and 6 biopsy samples revealed no evidence of malignancy. There were no major complications. Minor complications were recorded in 5 patients. CONCLUSION: Percutaneous image-guided core biopsy of mediastinal lesions is an accurate, safe and cost-effective tool for the initial assessment of patients with mediastinal masses. Medknow Publications 2008 /pmc/articles/PMC2700430/ /pubmed/19561877 http://dx.doi.org/10.4103/1817-1737.37948 Text en © Annals of Thoracic Medicine http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Kulkarni, Suyash
Kulkarni, Aniruddha
Roy, Diptiman
Thakur, Meenakshi H.
Percutaneous computed tomography-guided core biopsy for the diagnosis of mediastinal masses
title Percutaneous computed tomography-guided core biopsy for the diagnosis of mediastinal masses
title_full Percutaneous computed tomography-guided core biopsy for the diagnosis of mediastinal masses
title_fullStr Percutaneous computed tomography-guided core biopsy for the diagnosis of mediastinal masses
title_full_unstemmed Percutaneous computed tomography-guided core biopsy for the diagnosis of mediastinal masses
title_short Percutaneous computed tomography-guided core biopsy for the diagnosis of mediastinal masses
title_sort percutaneous computed tomography-guided core biopsy for the diagnosis of mediastinal masses
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700430/
https://www.ncbi.nlm.nih.gov/pubmed/19561877
http://dx.doi.org/10.4103/1817-1737.37948
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