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A new model for binding of kinesin 13 to curved microtubule protofilaments

Kinesin motor proteins use adenosine triphosphate hydrolysis to do work on microtubules (MTs). Most kinesins walk along the MT, but class 13 kinesins instead uniquely recognize MT ends and depolymerize MT protofilaments. We have used electron microscopy (EM) to understand the molecular interactions...

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Detalles Bibliográficos
Autores principales: Mulder, Anke M., Glavis-Bloom, Alex, Moores, Carolyn A., Wagenbach, Michael, Carragher, Bridget, Wordeman, Linda, Milligan, Ronald A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700504/
https://www.ncbi.nlm.nih.gov/pubmed/19332892
http://dx.doi.org/10.1083/jcb.200812052