Cargando…
A new model for binding of kinesin 13 to curved microtubule protofilaments
Kinesin motor proteins use adenosine triphosphate hydrolysis to do work on microtubules (MTs). Most kinesins walk along the MT, but class 13 kinesins instead uniquely recognize MT ends and depolymerize MT protofilaments. We have used electron microscopy (EM) to understand the molecular interactions...
Autores principales: | Mulder, Anke M., Glavis-Bloom, Alex, Moores, Carolyn A., Wagenbach, Michael, Carragher, Bridget, Wordeman, Linda, Milligan, Ronald A. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700504/ https://www.ncbi.nlm.nih.gov/pubmed/19332892 http://dx.doi.org/10.1083/jcb.200812052 |
Ejemplares similares
-
A kinesin-13 mutant catalytically depolymerizes microtubules in ADP
por: Wagenbach, Michael, et al.
Publicado: (2008) -
Kinesin follows the microtubule's protofilament axis
Publicado: (1993) -
MICROTUBULES: EVIDENCE FOR 13 PROTOFILAMENTS
por: Tilney, Lewis G., et al.
Publicado: (1973) -
Regulation of KinI kinesin ATPase activity by binding to the microtubule lattice
por: Moores, Carolyn A., et al.
Publicado: (2003) -
Divergent microtubule assembly rates after short- versus long-term loss of end-modulating kinesins
por: Wordeman, Linda, et al.
Publicado: (2016)