Cargando…
Angiogenin cleaves tRNA and promotes stress-induced translational repression
Stress-induced phosphorylation of eIF2α inhibits global protein synthesis to conserve energy for repair of stress-induced damage. Stress-induced translational arrest is observed in cells expressing a nonphosphorylatable eIF2α mutant (S51A), which indicates the existence of an alternative pathway of...
Autores principales: | Yamasaki, Satoshi, Ivanov, Pavel, Hu, Guo-fu, Anderson, Paul |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700517/ https://www.ncbi.nlm.nih.gov/pubmed/19332886 http://dx.doi.org/10.1083/jcb.200811106 |
Ejemplares similares
-
Angiogenin and tRNA fragments in Parkinson’s disease and neurodegeneration
por: Prehn, Jochen H M, et al.
Publicado: (2020) -
Vinca alkaloid drugs promote stress-induced translational repression and stress granule formation
por: Szaflarski, Witold, et al.
Publicado: (2016) -
NMR Characterization of Angiogenin Variants and tRNA(Ala) Products Impacting Aberrant Protein Oligomerization
por: Fagagnini, Andrea, et al.
Publicado: (2021) -
YB-1 regulates tiRNA-induced Stress Granule formation but not translational repression
por: Lyons, Shawn M., et al.
Publicado: (2016) -
RNase MRP Cleaves Pre-tRNA(Ser-Met) in the tRNA Maturation Pathway
por: Saito, Yuichiro, et al.
Publicado: (2014)