Cargando…

The Na(+)/H(+) exchanger NHE1 is required for directional migration stimulated via PDGFR-α in the primary cilium

We previously demonstrated that the primary cilium coordinates platelet-derived growth factor (PDGF) receptor (PDGFR) α–mediated migration in growth-arrested fibroblasts. In this study, we investigate the functional relationship between ciliary PDGFR-α and the Na(+)/H(+) exchanger NHE1 in directiona...

Descripción completa

Detalles Bibliográficos
Autores principales: Schneider, Linda, Stock, Christian-Martin, Dieterich, Peter, Jensen, Bo Hammer, Pedersen, Lotte Bang, Satir, Peter, Schwab, Albrecht, Christensen, Søren Tvorup, Pedersen, Stine Falsig
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700519/
https://www.ncbi.nlm.nih.gov/pubmed/19349585
http://dx.doi.org/10.1083/jcb.200806019