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Exportin 4 mediates a novel nuclear import pathway for Sox family transcription factors

SRY and other Sox-type transcription factors are important developmental regulators with various implications in human disease. In this study, we identified Exp4 (exportin 4) as an interaction partner of Sox2 in mouse embryonic stem cells and neural progenitors. We show that, besides its established...

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Detalles Bibliográficos
Autores principales: Gontan, Cristina, Güttler, Thomas, Engelen, Erik, Demmers, Jeroen, Fornerod, Maarten, Grosveld, Frank G., Tibboel, Dick, Görlich, Dirk, Poot, Raymond A., Rottier, Robbert J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700522/
https://www.ncbi.nlm.nih.gov/pubmed/19349578
http://dx.doi.org/10.1083/jcb.200810106