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Skin-Derived TSLP Triggers Progression from Epidermal-Barrier Defects to Asthma
Asthma is a common allergic lung disease frequently affecting individuals with a prior history of eczema/atopic dermatitis (AD); however, the mechanism underlying the progression from AD to asthma (the so-called “atopic march”) is unclear. Here we show that, like humans with AD, mice with skin-barri...
Autores principales: | Demehri, Shadmehr, Morimoto, Mitsuru, Holtzman, Michael J., Kopan, Raphael |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700555/ https://www.ncbi.nlm.nih.gov/pubmed/19557146 http://dx.doi.org/10.1371/journal.pbio.1000067 |
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