Overexpression of CCL-21/Secondary Lymphoid Tissue Chemokine in Human Dendritic Cells Augments Chemotactic Activities for Lymphocytes and Antigen Presenting Cells

BACKGROUND: Ex vivo generated dendritic cells (DC) genetically modified to express secondary lymphoid tissue chemokine (CCL-21/SLC) have been shown to stimulate potent antitumor responses in murine models. When injected intratumorally, CCL-21 colocalizes DC and lymphocyte effector cells at the tumor...

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Detalles Bibliográficos
Autores principales: Riedl, Karen, Baratelli, Felicita, Batra, Raj K, Yang, Seok Chul, Luo, Jie, Escuadro, Brian, Figlin, Robert, Strieter, Robert, Sharma, Sherven, Dubinett, Steven
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC270078/
https://www.ncbi.nlm.nih.gov/pubmed/14613584
http://dx.doi.org/10.1186/1476-4598-2-35

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