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Vascular endothelial growth factor regulates osteoblast survival – evidence for an autocrine feedback mechanism

BACKGROUND: Apoptosis of osteoblasts and osteoclasts regulates bone homeostasis. Skeletal injury in humans results in 'angiogenic' responses primarily mediated by vascular endothelial growth factor(VEGF), a protein essential for bone repair in animal models. Osteoblasts release VEGF in res...

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Detalles Bibliográficos
Autores principales: Street, John, Lenehan, Brian
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2701940/
https://www.ncbi.nlm.nih.gov/pubmed/19527527
http://dx.doi.org/10.1186/1749-799X-4-19

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