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Protein intrinsic disorder and influenza virulence: the 1918 H1N1 and H5N1 viruses

BACKGROUND: The 1918 H1N1 virus was a highly virulent strain that killed 20–50 million people. The cause of its virulence remains poorly understood. METHODS: Intrinsic disorder predictor PONDR(® )VLXT was used to compare various influenza subtypes and strains. Three-dimensional models using data fro...

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Detalles Bibliográficos
Autores principales: Goh, Gerard Kian-Meng, Dunker, A Keith, Uversky, Vladimir N
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2701943/
https://www.ncbi.nlm.nih.gov/pubmed/19493338
http://dx.doi.org/10.1186/1743-422X-6-69