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A common conformationally coupled ATPase mechanism for yeast and human cytoplasmic HSP90s
The conformationally coupled mechanism by which ATP is utilized by yeast Hsp90 is now well characterized. In contrast, ATP utilization by human Hsp90s is less well studied, and appears to operate differently. To resolve these conflicting models, we have conducted a side-by-side biochemical analysis...
Autores principales: | Vaughan, Cara K, Piper, Peter W, Pearl, Laurence H, Prodromou, Chrisostomos |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702006/ https://www.ncbi.nlm.nih.gov/pubmed/19032597 http://dx.doi.org/10.1111/j.1742-4658.2008.06773.x |
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