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Progesterone inhibition of MDM2 p90 protein in MCF-7 human breast cancer cell line is dependent on p53 levels

The mdm2 gene encodes several protein isoforms with different molecular weights (p90, p80, p76 and p57). MDM2 p90 (usually considered to be the major MDM2 protein) binds to and inactivates P53. We have recently shown that growth inhibition of MCF-7 human breast cancer cells by progesterone is associ...

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Detalles Bibliográficos
Autores principales: Alkhalaf, Moussa, El-Mowafy, Abdalla M, Abou-Zeid, Laila A
Formato: Texto
Lenguaje:English
Publicado: Library Publishing Media 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702060/
https://www.ncbi.nlm.nih.gov/pubmed/19565011

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