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Progesterone inhibition of MDM2 p90 protein in MCF-7 human breast cancer cell line is dependent on p53 levels
The mdm2 gene encodes several protein isoforms with different molecular weights (p90, p80, p76 and p57). MDM2 p90 (usually considered to be the major MDM2 protein) binds to and inactivates P53. We have recently shown that growth inhibition of MCF-7 human breast cancer cells by progesterone is associ...
Autores principales: | Alkhalaf, Moussa, El-Mowafy, Abdalla M, Abou-Zeid, Laila A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Library Publishing Media
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702060/ https://www.ncbi.nlm.nih.gov/pubmed/19565011 |
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