Evolutionary Dynamics of Human Toll-Like Receptors and Their Different Contributions to Host Defense

Infectious diseases have been paramount among the threats to health and survival throughout human evolutionary history. Natural selection is therefore expected to act strongly on host defense genes, particularly on innate immunity genes whose products mediate the direct interaction between the host...

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Detalles Bibliográficos
Autores principales: Barreiro, Luis B., Ben-Ali, Meriem, Quach, Hélène, Laval, Guillaume, Patin, Etienne, Pickrell, Joseph K., Bouchier, Christiane, Tichit, Magali, Neyrolles, Olivier, Gicquel, Brigitte, Kidd, Judith R., Kidd, Kenneth K., Alcaïs, Alexandre, Ragimbeau, Josiane, Pellegrini, Sandra, Abel, Laurent, Casanova, Jean-Laurent, Quintana-Murci, Lluís
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702086/
https://www.ncbi.nlm.nih.gov/pubmed/19609346
http://dx.doi.org/10.1371/journal.pgen.1000562

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