Fibrils from Designed Non-Amyloid-Related Synthetic Peptides Induce AA-Amyloidosis during Inflammation in an Animal Model

BACKGROUND: Mouse AA-amyloidosis is a transmissible disease by a prion-like mechanism where amyloid fibrils act by seeding. Synthetic peptides with no amyloid relationship can assemble into amyloid-like fibrils and these may have seeding capacity for amyloid proteins. PRINCIPAL FINDINGS: Several syn...

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Detalles Bibliográficos
Autores principales: Westermark, Per, Lundmark, Katarzyna, Westermark, Gunilla T.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702095/
https://www.ncbi.nlm.nih.gov/pubmed/19582162
http://dx.doi.org/10.1371/journal.pone.0006041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702095/
https://www.ncbi.nlm.nih.gov/pubmed/19582162
http://dx.doi.org/10.1371/journal.pone.0006041

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