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DNA Structure Modulates the Oligomerization Properties of the AAV Initiator Protein Rep68
Rep68 is a multifunctional protein of the adeno-associated virus (AAV), a parvovirus that is mostly known for its promise as a gene therapy vector. In addition to its role as initiator in viral DNA replication, Rep68 is essential for site-specific integration of the AAV genome into human chromosome...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702170/ https://www.ncbi.nlm.nih.gov/pubmed/19593381 http://dx.doi.org/10.1371/journal.ppat.1000513 |