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In situ aromatase expression in primary tumor is associated with estrogen receptor expression but is not predictive of response to endocrine therapy in advanced breast cancer

BACKGROUND: New, third-generation aromatase inhibitors (AIs) have proven comparable or superior to the anti-estrogen tamoxifen for treatment of estrogen receptor (ER) and/or progesterone receptor (PR) positive breast cancer. AIs suppress total body and intratumoral estrogen levels. It is unclear whe...

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Detalles Bibliográficos
Autores principales:	Lykkesfeldt, Anne E, Henriksen, Katrine L, Rasmussen, Birgitte B, Sasano, Hironobu, Evans, Dean B, Møller, Susanne, Ejlertsen, Bent, Mouridsen, Henning T
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702392/ https://www.ncbi.nlm.nih.gov/pubmed/19531212 http://dx.doi.org/10.1186/1471-2407-9-185

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