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Kif1b is essential for mRNA localization in oligodendrocytes and development of myelinated axons

The kinesin motor protein Kif1b has previously been implicated in the axonal transport of mitochondria and synaptic vesicles1,2. More recently kif1b has been linked with susceptibility to Multiple Sclerosis (MS) 3. Here we show that Kif1b is required for the localization of myelin basic protein mRNA...

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Detalles Bibliográficos
Autores principales: Lyons, David A., Naylor, Stephen G., Scholze, Anja, Talbot, William S.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702462/
https://www.ncbi.nlm.nih.gov/pubmed/19503091
http://dx.doi.org/10.1038/ng.376