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Talin 2 is a large and complex gene encoding multiple transcripts and protein isoforms
Talins are large adaptor proteins that link the integrin family of adhesion molecules to F-actin. In vertebrates, there are two talin genes. Talin 1 is essential for integrin-mediated cell adhesion; the role of talin 2 is unclear. Here we report a detailed analysis of mammalian talin 2. This reveals...
Autores principales: | Debrand, Emmanuel, El Jai, Yasmine, Spence, Lorraine, Bate, Neil, Praekelt, Uta, Pritchard, Catrin A, Monkley, Susan J, Critchley, David R |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702505/ https://www.ncbi.nlm.nih.gov/pubmed/19220457 http://dx.doi.org/10.1111/j.1742-4658.2009.06893.x |
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