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Granulocytic Sarcoma in the Head and Neck: CT and MR Imaging Findings
OBJECTIVES: To evaluate characteristic computed tomography (CT) and magnetic resonance (MR) imaging findings of granulocytic sarcomas of the head and neck. METHODS: The CT (n=11) and MR (n=1) images obtained from 11 patients (7 males and 4 females; mean age, 23.5 yr; age range, 1 to 69 yr) with hist...
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Formato: | Texto |
Lenguaje: | English |
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Korean Society of Otorhinolaryngology-Head and Neck Surgery
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702726/ https://www.ncbi.nlm.nih.gov/pubmed/19565030 http://dx.doi.org/10.3342/ceo.2009.2.2.66 |
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author | Noh, Bong Wan Park, Sun-Won Chun, Jung-Eun Kim, Ji Hye Kim, Hyung Jin Lim, Myung Kwan |
author_facet | Noh, Bong Wan Park, Sun-Won Chun, Jung-Eun Kim, Ji Hye Kim, Hyung Jin Lim, Myung Kwan |
author_sort | Noh, Bong Wan |
collection | PubMed |
description | OBJECTIVES: To evaluate characteristic computed tomography (CT) and magnetic resonance (MR) imaging findings of granulocytic sarcomas of the head and neck. METHODS: The CT (n=11) and MR (n=1) images obtained from 11 patients (7 males and 4 females; mean age, 23.5 yr; age range, 1 to 69 yr) with histologically-proven granulocytic sarcomas of the head and neck were retrospectively reviewed. Histological confirmation was done by bone marrow biopsy in 9 patients, and/or local biopsy in 4 patients. The imaging findings were analyzed with particular attention to location, size, shape, margin, bone destruction, internal architecture, pattern and degree of enhancement, and multiplicity of the lesions. RESULTS: The masses were most commonly located in the orbital cavity (n=8); other locations included lymph nodes (n=5) and palatine/pharyngeal/lingual tonsils (n=3). The mass sizes varied from a mean diameter of 1.3 to 5.8 cm (average, 2.6 cm). Multiple lesions were found in 6 patients. The shapes of the tumors were ovoid in 12 patients and irregular in 4 patients. Most lesions had poorly-defined margins (13/16) and invaded adjacent bony structures (5/16). On the pre-contrast CT images, the masses were iso- (5/8) or low-density (3/8) in comparison with muscle. The MRI, which was obtained in one patient in this study, showed that the mass was iso-signal intensity on T1-weighted images and iso-signal intensity on T2-weighted images compared to the gray matter of the brain. On the post-contrast CT images, there was homogenesous (n=12) or heterogeneous (n=4) enhancement, with mild (n=10), moderate (n=4), and marked (n=2) enhancement in the solid portions of the lesions. CONCLUSION: Although rare, granulocytic sarcomas arise in various locations in the head and neck area (most commonly in the orbit) in the form of well-demarcated, and mildly- and homogenously-enhancing masses with adjacent bony invasion. |
format | Text |
id | pubmed-2702726 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | Korean Society of Otorhinolaryngology-Head and Neck Surgery |
record_format | MEDLINE/PubMed |
spelling | pubmed-27027262009-06-29 Granulocytic Sarcoma in the Head and Neck: CT and MR Imaging Findings Noh, Bong Wan Park, Sun-Won Chun, Jung-Eun Kim, Ji Hye Kim, Hyung Jin Lim, Myung Kwan Clin Exp Otorhinolaryngol Original Article OBJECTIVES: To evaluate characteristic computed tomography (CT) and magnetic resonance (MR) imaging findings of granulocytic sarcomas of the head and neck. METHODS: The CT (n=11) and MR (n=1) images obtained from 11 patients (7 males and 4 females; mean age, 23.5 yr; age range, 1 to 69 yr) with histologically-proven granulocytic sarcomas of the head and neck were retrospectively reviewed. Histological confirmation was done by bone marrow biopsy in 9 patients, and/or local biopsy in 4 patients. The imaging findings were analyzed with particular attention to location, size, shape, margin, bone destruction, internal architecture, pattern and degree of enhancement, and multiplicity of the lesions. RESULTS: The masses were most commonly located in the orbital cavity (n=8); other locations included lymph nodes (n=5) and palatine/pharyngeal/lingual tonsils (n=3). The mass sizes varied from a mean diameter of 1.3 to 5.8 cm (average, 2.6 cm). Multiple lesions were found in 6 patients. The shapes of the tumors were ovoid in 12 patients and irregular in 4 patients. Most lesions had poorly-defined margins (13/16) and invaded adjacent bony structures (5/16). On the pre-contrast CT images, the masses were iso- (5/8) or low-density (3/8) in comparison with muscle. The MRI, which was obtained in one patient in this study, showed that the mass was iso-signal intensity on T1-weighted images and iso-signal intensity on T2-weighted images compared to the gray matter of the brain. On the post-contrast CT images, there was homogenesous (n=12) or heterogeneous (n=4) enhancement, with mild (n=10), moderate (n=4), and marked (n=2) enhancement in the solid portions of the lesions. CONCLUSION: Although rare, granulocytic sarcomas arise in various locations in the head and neck area (most commonly in the orbit) in the form of well-demarcated, and mildly- and homogenously-enhancing masses with adjacent bony invasion. Korean Society of Otorhinolaryngology-Head and Neck Surgery 2009-06 2009-06-27 /pmc/articles/PMC2702726/ /pubmed/19565030 http://dx.doi.org/10.3342/ceo.2009.2.2.66 Text en Copyright © 2009 Korean Society of Otorhinolaryngology-Head and Neck Surgery http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Noh, Bong Wan Park, Sun-Won Chun, Jung-Eun Kim, Ji Hye Kim, Hyung Jin Lim, Myung Kwan Granulocytic Sarcoma in the Head and Neck: CT and MR Imaging Findings |
title | Granulocytic Sarcoma in the Head and Neck: CT and MR Imaging Findings |
title_full | Granulocytic Sarcoma in the Head and Neck: CT and MR Imaging Findings |
title_fullStr | Granulocytic Sarcoma in the Head and Neck: CT and MR Imaging Findings |
title_full_unstemmed | Granulocytic Sarcoma in the Head and Neck: CT and MR Imaging Findings |
title_short | Granulocytic Sarcoma in the Head and Neck: CT and MR Imaging Findings |
title_sort | granulocytic sarcoma in the head and neck: ct and mr imaging findings |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702726/ https://www.ncbi.nlm.nih.gov/pubmed/19565030 http://dx.doi.org/10.3342/ceo.2009.2.2.66 |
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