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Clearing asymptomatic parasitaemia increases the specificity of the definition of mild febrile malaria

In clinical trials, the specificity of the disease endpoint is critical to an accurate estimate of vaccine efficacy. We used a logistic regression model to analyse parasite densities among children before and after treatment with antimalarials, in order to estimate the impact that clearing asymptoma...

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Detalles Bibliográficos
Autores principales: Bejon, Philip, Mwangi, Tabitha, Lowe, Brett, Peshu, Norbert, Hill, Adrian V.S., Marsh, Kevin
Formato: Texto
Lenguaje:English
Publicado: Elsevier Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702749/
https://www.ncbi.nlm.nih.gov/pubmed/17950960
http://dx.doi.org/10.1016/j.vaccine.2007.07.057