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Clearing asymptomatic parasitaemia increases the specificity of the definition of mild febrile malaria
In clinical trials, the specificity of the disease endpoint is critical to an accurate estimate of vaccine efficacy. We used a logistic regression model to analyse parasite densities among children before and after treatment with antimalarials, in order to estimate the impact that clearing asymptoma...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702749/ https://www.ncbi.nlm.nih.gov/pubmed/17950960 http://dx.doi.org/10.1016/j.vaccine.2007.07.057 |