Essential Roles of mTOR/Akt Pathway in Aurora-A Cell Transformation

We have recently demonstrated that Aurora-A kinase is a potential oncogene to develop mammary gland tumors in mice, when expressed under MMTV promoter. These tumors contain phosphorylated forms of Akt and mTOR, suggesting that Akt-mTOR pathway is involved in transformed phenotype induced by Aurora-A...

Descripción completa

Detalles Bibliográficos
Autores principales: Taga, Makoto, Hirooka, Eiji, Ouchi, Toru
Formato: Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2009
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702827/
https://www.ncbi.nlm.nih.gov/pubmed/19564927

Ejemplares similares

Ejemplares similares