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Induction of Thyroid Gene Expression and Radioiodine Uptake in Melanoma Cells: Novel Therapeutic Implications
Both the MAP kinase and PI3K/Akt pathways play an important role in the pathogenesis of melanoma. We conducted the present study to test the hypothesis that targeting the two pathways to potently induce cell inhibition accompanied with thyroid iodide-handling gene expression for adjunct radioiodine...
Autores principales: | Hou, Peng, Liu, Dingxie, Ji, Meiju, Liu, Zhi, Engles, James M., Wahl, Richard L., Xing, Mingzhao |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2703805/ https://www.ncbi.nlm.nih.gov/pubmed/19593429 http://dx.doi.org/10.1371/journal.pone.0006200 |
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