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GeneCodis: interpreting gene lists through enrichment analysis and integration of diverse biological information
GeneCodis is a web server application for functional analysis of gene lists that integrates different sources of information and finds modular patterns of interrelated annotations. This integrative approach has proved to be useful for the interpretation of high-throughput experiments and therefore a...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2703901/ https://www.ncbi.nlm.nih.gov/pubmed/19465387 http://dx.doi.org/10.1093/nar/gkp416 |
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author | Nogales-Cadenas, Ruben Carmona-Saez, Pedro Vazquez, Miguel Vicente, Cesar Yang, Xiaoyuan Tirado, Francisco Carazo, Jose María Pascual-Montano, Alberto |
author_facet | Nogales-Cadenas, Ruben Carmona-Saez, Pedro Vazquez, Miguel Vicente, Cesar Yang, Xiaoyuan Tirado, Francisco Carazo, Jose María Pascual-Montano, Alberto |
author_sort | Nogales-Cadenas, Ruben |
collection | PubMed |
description | GeneCodis is a web server application for functional analysis of gene lists that integrates different sources of information and finds modular patterns of interrelated annotations. This integrative approach has proved to be useful for the interpretation of high-throughput experiments and therefore a new version of the system has been developed to expand its functionality and scope. GeneCodis now expands the functional information with regulatory patterns and user-defined annotations, offering the possibility of integrating all sources of information in the same analysis. Traditional singular enrichment is now permitted and more organisms and gene identifiers have been added to the database. The application has been re-engineered to improve performance, accessibility and scalability. In addition, GeneCodis can now be accessed through a public SOAP web services interface, enabling users to perform analysis from their own scripts and workflows. The application is freely available at http://genecodis.dacya.ucm.es |
format | Text |
id | pubmed-2703901 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-27039012009-07-01 GeneCodis: interpreting gene lists through enrichment analysis and integration of diverse biological information Nogales-Cadenas, Ruben Carmona-Saez, Pedro Vazquez, Miguel Vicente, Cesar Yang, Xiaoyuan Tirado, Francisco Carazo, Jose María Pascual-Montano, Alberto Nucleic Acids Res Articles GeneCodis is a web server application for functional analysis of gene lists that integrates different sources of information and finds modular patterns of interrelated annotations. This integrative approach has proved to be useful for the interpretation of high-throughput experiments and therefore a new version of the system has been developed to expand its functionality and scope. GeneCodis now expands the functional information with regulatory patterns and user-defined annotations, offering the possibility of integrating all sources of information in the same analysis. Traditional singular enrichment is now permitted and more organisms and gene identifiers have been added to the database. The application has been re-engineered to improve performance, accessibility and scalability. In addition, GeneCodis can now be accessed through a public SOAP web services interface, enabling users to perform analysis from their own scripts and workflows. The application is freely available at http://genecodis.dacya.ucm.es Oxford University Press 2009-07-01 2009-05-22 /pmc/articles/PMC2703901/ /pubmed/19465387 http://dx.doi.org/10.1093/nar/gkp416 Text en © 2009 The Author(s) http://creativecommons.org/licenses/by-nc/2.0/uk/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Articles Nogales-Cadenas, Ruben Carmona-Saez, Pedro Vazquez, Miguel Vicente, Cesar Yang, Xiaoyuan Tirado, Francisco Carazo, Jose María Pascual-Montano, Alberto GeneCodis: interpreting gene lists through enrichment analysis and integration of diverse biological information |
title | GeneCodis: interpreting gene lists through enrichment analysis and integration of diverse biological information |
title_full | GeneCodis: interpreting gene lists through enrichment analysis and integration of diverse biological information |
title_fullStr | GeneCodis: interpreting gene lists through enrichment analysis and integration of diverse biological information |
title_full_unstemmed | GeneCodis: interpreting gene lists through enrichment analysis and integration of diverse biological information |
title_short | GeneCodis: interpreting gene lists through enrichment analysis and integration of diverse biological information |
title_sort | genecodis: interpreting gene lists through enrichment analysis and integration of diverse biological information |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2703901/ https://www.ncbi.nlm.nih.gov/pubmed/19465387 http://dx.doi.org/10.1093/nar/gkp416 |
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