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Maternal administration of anti-angiogenic agents, TNP-470 and Angiostatin(4.5), induces fetal microphthalmia
PURPOSE: Agents specifically targeting the vasculature as a mode of therapy are finding increasing use in the clinic, primarily in the treatment of colon cancer (Avastin™) and age-related macular degeneration (Lucentis™). We have previously shown that maternal administration of angiogenic inhibitors...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Molecular Vision
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704144/ https://www.ncbi.nlm.nih.gov/pubmed/19572040 |