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Effective suppression of Dengue fever virus in mosquito cell cultures using retroviral transduction of hammerhead ribozymes targeting the viral genome

Outbreaks of Dengue impose a heavy economic burden on developing countries in terms of vector control and human morbidity. Effective vaccines against all four serotypes of Dengue are in development, but population replacement with transgenic vectors unable to transmit the virus might ultimately prov...

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Detalles Bibliográficos
Autores principales: Nawtaisong, Pruksa, Keith, James, Fraser, Tresa, Balaraman, Velmurugan, Kolokoltsov, Andrey, Davey, Robert A, Higgs, Stephen, Mohammed, Ahmed, Rongsriyam, Yupha, Komalamisra, Narumon, Fraser, Malcolm J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704196/
https://www.ncbi.nlm.nih.gov/pubmed/19497123
http://dx.doi.org/10.1186/1743-422X-6-73