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Effective suppression of Dengue fever virus in mosquito cell cultures using retroviral transduction of hammerhead ribozymes targeting the viral genome
Outbreaks of Dengue impose a heavy economic burden on developing countries in terms of vector control and human morbidity. Effective vaccines against all four serotypes of Dengue are in development, but population replacement with transgenic vectors unable to transmit the virus might ultimately prov...
Autores principales: | Nawtaisong, Pruksa, Keith, James, Fraser, Tresa, Balaraman, Velmurugan, Kolokoltsov, Andrey, Davey, Robert A, Higgs, Stephen, Mohammed, Ahmed, Rongsriyam, Yupha, Komalamisra, Narumon, Fraser, Malcolm J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704196/ https://www.ncbi.nlm.nih.gov/pubmed/19497123 http://dx.doi.org/10.1186/1743-422X-6-73 |
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