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Characterization of α-isopropylmalate synthases containing different copy numbers of tandem repeats in Mycobacterium tuberculosis

BACKGROUND: Alpha-isopropylmalate synthase (α-IPMS) is the key enzyme that catalyzes the first committed step in the leucine biosynthetic pathway. The gene encoding α-IPMS in Mycobacterium tuberculosis, leuA, is polymorphic due to the insertion of 57-bp repeat units referred to as Variable Number of...

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Detalles Bibliográficos
Autores principales:	Yindeeyoungyeon, Wandee, Likitvivatanavong, Supaporn, Palittapongarnpim, Prasit
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704214/ https://www.ncbi.nlm.nih.gov/pubmed/19505340 http://dx.doi.org/10.1186/1471-2180-9-122

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