Deoxycholate induces COX-2 expression via Erk1/2-, p38-MAPK and AP-1-dependent mechanisms in esophageal cancer cells

BACKGROUND: The progression from Barrett's metaplasia to adenocarcinoma is associated with the acquirement of an apoptosis-resistant phenotype. The bile acid deoxycholate (DCA) has been proposed to play an important role in the development of esophageal adenocarcinoma, but the precise molecular...

Descripción completa

Detalles Bibliográficos
Autores principales: Looby, Eileen, Abdel-Latif, Mohamed MM, Athié-Morales, Veronica, Duggan, Shane, Long, Aideen, Kelleher, Dermot
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704223/
https://www.ncbi.nlm.nih.gov/pubmed/19534809
http://dx.doi.org/10.1186/1471-2407-9-190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704223/
https://www.ncbi.nlm.nih.gov/pubmed/19534809
http://dx.doi.org/10.1186/1471-2407-9-190

Ejemplares similares