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Biophysical Mechanism for Ras-Nanocluster Formation and Signaling in Plasma Membrane
Ras GTPases are lipid-anchored G proteins, which play a fundamental role in cell signaling processes. Electron micrographs of immunogold-labeled Ras have shown that membrane-bound Ras molecules segregate into nanocluster domains. Several models have been developed in attempts to obtain quantitative...
Autores principales: | Gurry, Thomas, Kahramanoğulları, Ozan, Endres, Robert G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704371/ https://www.ncbi.nlm.nih.gov/pubmed/19587789 http://dx.doi.org/10.1371/journal.pone.0006148 |
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