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Urinary tract infections in children after renal transplantation

Urinary tract infections (UTI) after pediatric kidney transplantation (KTX) are an important clinical problem and occur in 15–33% of patients. Febrile UTI, whether occurring in the transplanted kidney or the native kidney, should be differentiated from afebrile UTI. The latter may cause significant...

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Autores principales: John, Ulrike, Kemper, Markus J.
Formato: Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704952/
https://www.ncbi.nlm.nih.gov/pubmed/18197424
http://dx.doi.org/10.1007/s00467-007-0690-0
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author John, Ulrike
Kemper, Markus J.
author_facet John, Ulrike
Kemper, Markus J.
author_sort John, Ulrike
collection PubMed
description Urinary tract infections (UTI) after pediatric kidney transplantation (KTX) are an important clinical problem and occur in 15–33% of patients. Febrile UTI, whether occurring in the transplanted kidney or the native kidney, should be differentiated from afebrile UTI. The latter may cause significant morbidity and is usually associated with acute graft dysfunction. Risk factors for (febrile) UTI include anatomical, functional, and demographic factors as well as baseline immunosuppression and foreign material, such as catheters and stents. Meticulous surveillance, diagnosis, and treatment of UTI is important to minimize acute morbidity and compromise of long-term graft function. In febrile UTI, parenteral antibiotics are usually indicated, although controlled data are not available. As most data concerning UTI have been accumulated retrospectively, future prospective studies have to be performed to clarify pathogenetic mechanisms and risk factors, improve prophylaxis and treatment, and ultimately optimize long-term renal graft survival.
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spelling pubmed-27049522009-07-02 Urinary tract infections in children after renal transplantation John, Ulrike Kemper, Markus J. Pediatr Nephrol Educational Feature Urinary tract infections (UTI) after pediatric kidney transplantation (KTX) are an important clinical problem and occur in 15–33% of patients. Febrile UTI, whether occurring in the transplanted kidney or the native kidney, should be differentiated from afebrile UTI. The latter may cause significant morbidity and is usually associated with acute graft dysfunction. Risk factors for (febrile) UTI include anatomical, functional, and demographic factors as well as baseline immunosuppression and foreign material, such as catheters and stents. Meticulous surveillance, diagnosis, and treatment of UTI is important to minimize acute morbidity and compromise of long-term graft function. In febrile UTI, parenteral antibiotics are usually indicated, although controlled data are not available. As most data concerning UTI have been accumulated retrospectively, future prospective studies have to be performed to clarify pathogenetic mechanisms and risk factors, improve prophylaxis and treatment, and ultimately optimize long-term renal graft survival. Springer Berlin Heidelberg 2009-06-01 2009 /pmc/articles/PMC2704952/ /pubmed/18197424 http://dx.doi.org/10.1007/s00467-007-0690-0 Text en © IPNA 2007 This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Educational Feature
John, Ulrike
Kemper, Markus J.
Urinary tract infections in children after renal transplantation
title Urinary tract infections in children after renal transplantation
title_full Urinary tract infections in children after renal transplantation
title_fullStr Urinary tract infections in children after renal transplantation
title_full_unstemmed Urinary tract infections in children after renal transplantation
title_short Urinary tract infections in children after renal transplantation
title_sort urinary tract infections in children after renal transplantation
topic Educational Feature
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704952/
https://www.ncbi.nlm.nih.gov/pubmed/18197424
http://dx.doi.org/10.1007/s00467-007-0690-0
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