Identification of a Kinase Profile that Predicts Chromosome Damage Induced by Small Molecule Kinase Inhibitors

Kinases are heavily pursued pharmaceutical targets because of their mechanistic role in many diseases. Small molecule kinase inhibitors (SMKIs) are a compound class that includes marketed drugs and compounds in various stages of drug development. While effective, many SMKIs have been associated with...

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Detalles Bibliográficos
Autores principales: Olaharski, Andrew J., Gonzaludo, Nina, Bitter, Hans, Goldstein, David, Kirchner, Stephan, Uppal, Hirdesh, Kolaja, Kyle
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704959/
https://www.ncbi.nlm.nih.gov/pubmed/19629159
http://dx.doi.org/10.1371/journal.pcbi.1000446

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