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Cellular Contractility Requires Ubiquitin Mediated Proteolysis

BACKGROUND: Cellular contractility, essential for cell movement and proliferation, is regulated by microtubules, RhoA and actomyosin. The RhoA dependent kinase ROCK ensures the phosphorylation of the regulatory Myosin II Light Chain (MLC) Ser19, thereby activating actomyosin contractions. Microtubul...

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Detalles Bibliográficos
Autores principales:	Cinnamon, Yuval, Feine, Oren, Hochegger, Helfrid, Bershadsky, Alexander, Brandeis, Michael
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705188/ https://www.ncbi.nlm.nih.gov/pubmed/19597551 http://dx.doi.org/10.1371/journal.pone.0006155

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