Novel mutations in TLR genes cause hyporesponsiveness to Mycobacterium avium subsp. paratuberculosis infection

BACKGROUND: Toll like receptors (TLR) play the central role in the recognition of pathogen associated molecular patterns (PAMPs). Mutations in the TLR1, TLR2 and TLR4 genes may change the ability to recognize PAMPs and cause altered responsiveness to the bacterial pathogens. RESULTS: The study prese...

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Detalles Bibliográficos
Autores principales: Bhide, Mangesh R, Mucha, Rastislav, Mikula, Ivan, Kisova, Lucia, Skrabana, Rostislav, Novak, Michal
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705378/
https://www.ncbi.nlm.nih.gov/pubmed/19470169
http://dx.doi.org/10.1186/1471-2156-10-21

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