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Prediction error variance and expected response to selection, when selection is based on the best predictor – for Gaussian and threshold characters, traits following a Poisson mixed model and survival traits

In this paper, we consider selection based on the best predictor of animal additive genetic values in Gaussian linear mixed models, threshold models, Poisson mixed models, and log normal frailty models for survival data (including models with time-dependent covariates with associated fixed or random...

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Detalles Bibliográficos
Autores principales: Korsgaard, Inge Riis, Andersen, Anders Holst, Jensen, Just
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705448/
https://www.ncbi.nlm.nih.gov/pubmed/12081800
http://dx.doi.org/10.1186/1297-9686-34-3-307
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author Korsgaard, Inge Riis
Andersen, Anders Holst
Jensen, Just
author_facet Korsgaard, Inge Riis
Andersen, Anders Holst
Jensen, Just
author_sort Korsgaard, Inge Riis
collection PubMed
description In this paper, we consider selection based on the best predictor of animal additive genetic values in Gaussian linear mixed models, threshold models, Poisson mixed models, and log normal frailty models for survival data (including models with time-dependent covariates with associated fixed or random effects). In the different models, expressions are given (when these can be found – otherwise unbiased estimates are given) for prediction error variance, accuracy of selection and expected response to selection on the additive genetic scale and on the observed scale. The expressions given for non Gaussian traits are generalisations of the well-known formulas for Gaussian traits – and reflect, for Poisson mixed models and frailty models for survival data, the hierarchal structure of the models. In general the ratio of the additive genetic variance to the total variance in the Gaussian part of the model (heritability on the normally distributed level of the model) or a generalised version of heritability plays a central role in these formulas.
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spelling pubmed-27054482009-07-03 Prediction error variance and expected response to selection, when selection is based on the best predictor – for Gaussian and threshold characters, traits following a Poisson mixed model and survival traits Korsgaard, Inge Riis Andersen, Anders Holst Jensen, Just Genet Sel Evol Research In this paper, we consider selection based on the best predictor of animal additive genetic values in Gaussian linear mixed models, threshold models, Poisson mixed models, and log normal frailty models for survival data (including models with time-dependent covariates with associated fixed or random effects). In the different models, expressions are given (when these can be found – otherwise unbiased estimates are given) for prediction error variance, accuracy of selection and expected response to selection on the additive genetic scale and on the observed scale. The expressions given for non Gaussian traits are generalisations of the well-known formulas for Gaussian traits – and reflect, for Poisson mixed models and frailty models for survival data, the hierarchal structure of the models. In general the ratio of the additive genetic variance to the total variance in the Gaussian part of the model (heritability on the normally distributed level of the model) or a generalised version of heritability plays a central role in these formulas. BioMed Central 2002-05-15 /pmc/articles/PMC2705448/ /pubmed/12081800 http://dx.doi.org/10.1186/1297-9686-34-3-307 Text en Copyright © 2002 INRA, EDP Sciences
spellingShingle Research
Korsgaard, Inge Riis
Andersen, Anders Holst
Jensen, Just
Prediction error variance and expected response to selection, when selection is based on the best predictor – for Gaussian and threshold characters, traits following a Poisson mixed model and survival traits
title Prediction error variance and expected response to selection, when selection is based on the best predictor – for Gaussian and threshold characters, traits following a Poisson mixed model and survival traits
title_full Prediction error variance and expected response to selection, when selection is based on the best predictor – for Gaussian and threshold characters, traits following a Poisson mixed model and survival traits
title_fullStr Prediction error variance and expected response to selection, when selection is based on the best predictor – for Gaussian and threshold characters, traits following a Poisson mixed model and survival traits
title_full_unstemmed Prediction error variance and expected response to selection, when selection is based on the best predictor – for Gaussian and threshold characters, traits following a Poisson mixed model and survival traits
title_short Prediction error variance and expected response to selection, when selection is based on the best predictor – for Gaussian and threshold characters, traits following a Poisson mixed model and survival traits
title_sort prediction error variance and expected response to selection, when selection is based on the best predictor – for gaussian and threshold characters, traits following a poisson mixed model and survival traits
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705448/
https://www.ncbi.nlm.nih.gov/pubmed/12081800
http://dx.doi.org/10.1186/1297-9686-34-3-307
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