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Prediction error variance and expected response to selection, when selection is based on the best predictor – for Gaussian and threshold characters, traits following a Poisson mixed model and survival traits
In this paper, we consider selection based on the best predictor of animal additive genetic values in Gaussian linear mixed models, threshold models, Poisson mixed models, and log normal frailty models for survival data (including models with time-dependent covariates with associated fixed or random...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705448/ https://www.ncbi.nlm.nih.gov/pubmed/12081800 http://dx.doi.org/10.1186/1297-9686-34-3-307 |
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author | Korsgaard, Inge Riis Andersen, Anders Holst Jensen, Just |
author_facet | Korsgaard, Inge Riis Andersen, Anders Holst Jensen, Just |
author_sort | Korsgaard, Inge Riis |
collection | PubMed |
description | In this paper, we consider selection based on the best predictor of animal additive genetic values in Gaussian linear mixed models, threshold models, Poisson mixed models, and log normal frailty models for survival data (including models with time-dependent covariates with associated fixed or random effects). In the different models, expressions are given (when these can be found – otherwise unbiased estimates are given) for prediction error variance, accuracy of selection and expected response to selection on the additive genetic scale and on the observed scale. The expressions given for non Gaussian traits are generalisations of the well-known formulas for Gaussian traits – and reflect, for Poisson mixed models and frailty models for survival data, the hierarchal structure of the models. In general the ratio of the additive genetic variance to the total variance in the Gaussian part of the model (heritability on the normally distributed level of the model) or a generalised version of heritability plays a central role in these formulas. |
format | Text |
id | pubmed-2705448 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2002 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-27054482009-07-03 Prediction error variance and expected response to selection, when selection is based on the best predictor – for Gaussian and threshold characters, traits following a Poisson mixed model and survival traits Korsgaard, Inge Riis Andersen, Anders Holst Jensen, Just Genet Sel Evol Research In this paper, we consider selection based on the best predictor of animal additive genetic values in Gaussian linear mixed models, threshold models, Poisson mixed models, and log normal frailty models for survival data (including models with time-dependent covariates with associated fixed or random effects). In the different models, expressions are given (when these can be found – otherwise unbiased estimates are given) for prediction error variance, accuracy of selection and expected response to selection on the additive genetic scale and on the observed scale. The expressions given for non Gaussian traits are generalisations of the well-known formulas for Gaussian traits – and reflect, for Poisson mixed models and frailty models for survival data, the hierarchal structure of the models. In general the ratio of the additive genetic variance to the total variance in the Gaussian part of the model (heritability on the normally distributed level of the model) or a generalised version of heritability plays a central role in these formulas. BioMed Central 2002-05-15 /pmc/articles/PMC2705448/ /pubmed/12081800 http://dx.doi.org/10.1186/1297-9686-34-3-307 Text en Copyright © 2002 INRA, EDP Sciences |
spellingShingle | Research Korsgaard, Inge Riis Andersen, Anders Holst Jensen, Just Prediction error variance and expected response to selection, when selection is based on the best predictor – for Gaussian and threshold characters, traits following a Poisson mixed model and survival traits |
title | Prediction error variance and expected response to selection, when selection is based on the best predictor – for Gaussian and threshold characters, traits following a Poisson mixed model and survival traits |
title_full | Prediction error variance and expected response to selection, when selection is based on the best predictor – for Gaussian and threshold characters, traits following a Poisson mixed model and survival traits |
title_fullStr | Prediction error variance and expected response to selection, when selection is based on the best predictor – for Gaussian and threshold characters, traits following a Poisson mixed model and survival traits |
title_full_unstemmed | Prediction error variance and expected response to selection, when selection is based on the best predictor – for Gaussian and threshold characters, traits following a Poisson mixed model and survival traits |
title_short | Prediction error variance and expected response to selection, when selection is based on the best predictor – for Gaussian and threshold characters, traits following a Poisson mixed model and survival traits |
title_sort | prediction error variance and expected response to selection, when selection is based on the best predictor – for gaussian and threshold characters, traits following a poisson mixed model and survival traits |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705448/ https://www.ncbi.nlm.nih.gov/pubmed/12081800 http://dx.doi.org/10.1186/1297-9686-34-3-307 |
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