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Sequential Allocation to Balance Prognostic Factors in a Psychiatric Clinical Trial
OBJECTIVE: This paper aims to describe and discuss a minimization procedure specifically designed for a clinical trial that evaluates treatment efficacy for OCD patients. METHOD: Aitchison’s compositional distance was used to calculate vectors for each possibility of allocation in a covariate adapti...
Autores principales: | Fossaluza, Victor, Diniz, Juliana Belo, de Bragança Pereira, Basilio, Miguel, Eurípedes Constantino, de Bragança Pereira, Carlos Alberto |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705482/ https://www.ncbi.nlm.nih.gov/pubmed/19578654 http://dx.doi.org/10.1590/S1807-59322009000600005 |
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