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Cooperativity Dominates the Genomic Organization of p53-Response Elements: A Mechanistic View
p53-response elements (p53-REs) are organized as two repeats of a palindromic DNA segment spaced by 0 to 20 base pairs (bp). Several experiments indicate that in the vast majority of the human p53-REs there are no spacers between the two repeats; those with spacers, particularly with sizes beyond tw...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705680/ https://www.ncbi.nlm.nih.gov/pubmed/19629163 http://dx.doi.org/10.1371/journal.pcbi.1000448 |