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New Target Genes for the Peroxisome Proliferator-Activated Receptor-γ (PPARγ) Antitumour Activity: Perspectives from the Insulin Receptor
The insulin receptor (IR) plays a crucial role in mediating the metabolic and proliferative functions triggered by the peptide hormone insulin. There is considerable evidence that abnormalities in both IR expression and function may account for malignant transformation and tumour progression in some...
Autores principales: | Foti, Daniela P., Paonessa, Francesco, Chiefari, Eusebio, Brunetti, Antonio |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705764/ https://www.ncbi.nlm.nih.gov/pubmed/19587804 http://dx.doi.org/10.1155/2009/571365 |
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