Effectiveness of Rituximab in Severe Wegener’s Granulomatosis: Report of Two Cases and Review of the Literature

We hereby describe the satisfactory evolution of rituximab treatment in two patients with Wegener’s granulomatosis (WG). Rituximab was indicated for refractoriness to standard treatment in one case and life-threatening myelotoxicity due to alkylating agents in the other. A brief review of previous e...

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Autores principales: Oristrell, Joaquim, Bejarano, Guillermina, Jordana, Rosa, Monteagudo, Manuel, Marí, Begoña, Casanovas, Arnau, Tolosa, Carles
Formato: Texto
Lenguaje:English
Publicado: Bentham Open 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705845/
https://www.ncbi.nlm.nih.gov/pubmed/19590594
http://dx.doi.org/10.2174/1874306400903010094
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author Oristrell, Joaquim
Bejarano, Guillermina
Jordana, Rosa
Monteagudo, Manuel
Marí, Begoña
Casanovas, Arnau
Tolosa, Carles
author_facet Oristrell, Joaquim
Bejarano, Guillermina
Jordana, Rosa
Monteagudo, Manuel
Marí, Begoña
Casanovas, Arnau
Tolosa, Carles
author_sort Oristrell, Joaquim
collection PubMed
description We hereby describe the satisfactory evolution of rituximab treatment in two patients with Wegener’s granulomatosis (WG). Rituximab was indicated for refractoriness to standard treatment in one case and life-threatening myelotoxicity due to alkylating agents in the other. A brief review of previous experience with the use of rituximab in the treatment of WG is presented.
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spelling pubmed-27058452009-07-09 Effectiveness of Rituximab in Severe Wegener’s Granulomatosis: Report of Two Cases and Review of the Literature Oristrell, Joaquim Bejarano, Guillermina Jordana, Rosa Monteagudo, Manuel Marí, Begoña Casanovas, Arnau Tolosa, Carles Open Respir Med J Article We hereby describe the satisfactory evolution of rituximab treatment in two patients with Wegener’s granulomatosis (WG). Rituximab was indicated for refractoriness to standard treatment in one case and life-threatening myelotoxicity due to alkylating agents in the other. A brief review of previous experience with the use of rituximab in the treatment of WG is presented. Bentham Open 2009-06-25 /pmc/articles/PMC2705845/ /pubmed/19590594 http://dx.doi.org/10.2174/1874306400903010094 Text en © Oristrell et al.; Licensee Bentham Open. http://creativecommons.org/licenses/by-nc/3.0/ This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
spellingShingle Article
Oristrell, Joaquim
Bejarano, Guillermina
Jordana, Rosa
Monteagudo, Manuel
Marí, Begoña
Casanovas, Arnau
Tolosa, Carles
Effectiveness of Rituximab in Severe Wegener’s Granulomatosis: Report of Two Cases and Review of the Literature
title Effectiveness of Rituximab in Severe Wegener’s Granulomatosis: Report of Two Cases and Review of the Literature
title_full Effectiveness of Rituximab in Severe Wegener’s Granulomatosis: Report of Two Cases and Review of the Literature
title_fullStr Effectiveness of Rituximab in Severe Wegener’s Granulomatosis: Report of Two Cases and Review of the Literature
title_full_unstemmed Effectiveness of Rituximab in Severe Wegener’s Granulomatosis: Report of Two Cases and Review of the Literature
title_short Effectiveness of Rituximab in Severe Wegener’s Granulomatosis: Report of Two Cases and Review of the Literature
title_sort effectiveness of rituximab in severe wegener’s granulomatosis: report of two cases and review of the literature
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705845/
https://www.ncbi.nlm.nih.gov/pubmed/19590594
http://dx.doi.org/10.2174/1874306400903010094
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