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Altered effector function of peripheral cytotoxic cells in COPD

BACKGROUND: There is mounting evidence that perforin and granzymes are important mediators in the lung destruction seen in COPD. We investigated the characteristics of the three main perforin and granzyme containing peripheral cells, namely CD8(+ )T lymphocytes, natural killer (NK; CD56(+)CD3(-)) ce...

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Detalles Bibliográficos
Autores principales:	Urbanowicz, Richard A, Lamb, Jonathan R, Todd, Ian, Corne, Jonathan M, Fairclough, Lucy C
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705911/ https://www.ncbi.nlm.nih.gov/pubmed/19545425 http://dx.doi.org/10.1186/1465-9921-10-53

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