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An ENU-induced mutation of miR-96 associated with progressive hearing loss in mice
Progressive hearing loss is common in the human population, but little is known about the molecular basis. We report a new ENU-induced mouse mutant, diminuendo, with a single base change in the seed region of Mirn96. Heterozygotes show progressive loss of hearing and hair cell anomalies, while homoz...
| Autores principales: | , , , , , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705913/ https://www.ncbi.nlm.nih.gov/pubmed/19363478 http://dx.doi.org/10.1038/ng.369 |