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Poisoned patients as potential organ donors: postal survey of transplant centres and intensive care units

BACKGROUND: The number of patients awaiting allograft transplantation in the UK exceeds the number of organs offered for transplantation each year. Most organ donors tend to be young, fit and healthy individuals who die because of trauma or sudden cardiac arrest. Patients who die from drug and poiso...

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Autores principales: Wood, David Michael, Dargan, Paul Ivor, Jones, Alison Linda
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC270623/
https://www.ncbi.nlm.nih.gov/pubmed/12720561
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author Wood, David Michael
Dargan, Paul Ivor
Jones, Alison Linda
author_facet Wood, David Michael
Dargan, Paul Ivor
Jones, Alison Linda
author_sort Wood, David Michael
collection PubMed
description BACKGROUND: The number of patients awaiting allograft transplantation in the UK exceeds the number of organs offered for transplantation each year. Most organ donors tend to be young, fit and healthy individuals who die because of trauma or sudden cardiac arrest. Patients who die from drug and poison intoxication tend to have similar characteristics but are less frequently offered as potential organ donors. METHODS: A postal questionnaire survey of all transplantation centres and an equal number of intensive care units in the UK was undertaken. The use of kidney, heart, lung, liver and pancreas transplants from poisoned patients following deliberate methanol ingestion, cardiac arrest presumed secondary to cocaine overdose, accidental domestic carbon monoxide inhalation and industrial cyanide exposure were used as case scenarios. RESULTS: Response rates were 70% for transplantation centres and 50% for intensive care unit directors. Over 80% of organs would be offered or discussed with transplant coordinators by intensive care unit directors. Transplantation physicians/surgeons would consider transplanting organs in up to 100% of case scenarios, depending on the organ and poisoning or intoxication involved. DISCUSSION: The postal survey presented here shows that most transplantation physicians and surgeons and intensive care unit directors would consider those who die following acute drug intoxication and poisoning as potential organ donors. The previously reported literature shows in general that transplanted organs from poisoned patients have good long-term survival, although the number of reports is small. Poisoned patients are another pool of organ donors who at present are probably underused by transplantation services.
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spelling pubmed-2706232003-11-21 Poisoned patients as potential organ donors: postal survey of transplant centres and intensive care units Wood, David Michael Dargan, Paul Ivor Jones, Alison Linda Crit Care Research BACKGROUND: The number of patients awaiting allograft transplantation in the UK exceeds the number of organs offered for transplantation each year. Most organ donors tend to be young, fit and healthy individuals who die because of trauma or sudden cardiac arrest. Patients who die from drug and poison intoxication tend to have similar characteristics but are less frequently offered as potential organ donors. METHODS: A postal questionnaire survey of all transplantation centres and an equal number of intensive care units in the UK was undertaken. The use of kidney, heart, lung, liver and pancreas transplants from poisoned patients following deliberate methanol ingestion, cardiac arrest presumed secondary to cocaine overdose, accidental domestic carbon monoxide inhalation and industrial cyanide exposure were used as case scenarios. RESULTS: Response rates were 70% for transplantation centres and 50% for intensive care unit directors. Over 80% of organs would be offered or discussed with transplant coordinators by intensive care unit directors. Transplantation physicians/surgeons would consider transplanting organs in up to 100% of case scenarios, depending on the organ and poisoning or intoxication involved. DISCUSSION: The postal survey presented here shows that most transplantation physicians and surgeons and intensive care unit directors would consider those who die following acute drug intoxication and poisoning as potential organ donors. The previously reported literature shows in general that transplanted organs from poisoned patients have good long-term survival, although the number of reports is small. Poisoned patients are another pool of organ donors who at present are probably underused by transplantation services. BioMed Central 2003 2003-03-06 /pmc/articles/PMC270623/ /pubmed/12720561 Text en Copyright © 2003 Wood et al., licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL.
spellingShingle Research
Wood, David Michael
Dargan, Paul Ivor
Jones, Alison Linda
Poisoned patients as potential organ donors: postal survey of transplant centres and intensive care units
title Poisoned patients as potential organ donors: postal survey of transplant centres and intensive care units
title_full Poisoned patients as potential organ donors: postal survey of transplant centres and intensive care units
title_fullStr Poisoned patients as potential organ donors: postal survey of transplant centres and intensive care units
title_full_unstemmed Poisoned patients as potential organ donors: postal survey of transplant centres and intensive care units
title_short Poisoned patients as potential organ donors: postal survey of transplant centres and intensive care units
title_sort poisoned patients as potential organ donors: postal survey of transplant centres and intensive care units
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC270623/
https://www.ncbi.nlm.nih.gov/pubmed/12720561
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