The INSIG2 rs7566605 genetic variant does not play a major role in obesity in a sample of 24,722 individuals from four cohorts

BACKGROUND: In a genome-wide association study performed in the Framingham Offspring Cohort, individuals homozygous for the rs7566605 C allele located upstream of insulin-induced gene 2 (INSIG2) were reported to incur an increased risk of obesity. This finding was later replicated in four out of fiv...

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Detalles Bibliográficos
Autores principales: Bressler, Jan, Fornage, Myriam, Hanis, Craig L, Kao, Wen Hong Linda, Lewis, Cora E, McPherson, Ruth, Dent, Robert, Mosley, Thomas H, Pennacchio, Len A, Boerwinkle, Eric
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706232/
https://www.ncbi.nlm.nih.gov/pubmed/19523229
http://dx.doi.org/10.1186/1471-2350-10-56

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