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Folding versus aggregation: Polypeptide conformations on competing pathways

Protein aggregation has now become recognised as an important and generic aspect of protein energy landscapes. Since the discovery that numerous human diseases are caused by protein aggregation, the biophysical characterisation of misfolded states and their aggregation mechanisms has received increa...

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Detalles Bibliográficos
Autores principales: Jahn, Thomas R., Radford, Sheena E.
Formato: Texto
Lenguaje:English
Publicado: Academic Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706318/
https://www.ncbi.nlm.nih.gov/pubmed/17588526
http://dx.doi.org/10.1016/j.abb.2007.05.015