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Folding versus aggregation: Polypeptide conformations on competing pathways
Protein aggregation has now become recognised as an important and generic aspect of protein energy landscapes. Since the discovery that numerous human diseases are caused by protein aggregation, the biophysical characterisation of misfolded states and their aggregation mechanisms has received increa...
Autores principales: | Jahn, Thomas R., Radford, Sheena E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706318/ https://www.ncbi.nlm.nih.gov/pubmed/17588526 http://dx.doi.org/10.1016/j.abb.2007.05.015 |
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