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Monitoring Copopulated Conformational States During Protein Folding Events Using Electrospray Ionization-Ion Mobility Spectrometry-Mass Spectrometry
The precise mechanism of protein folding remains elusive and there is a deficiency of biophysical techniques that are capable of monitoring the individual behavior of copopulated protein conformers during the folding process. Herein, an ion mobility spectrometry (IMS) device integrated with electros...
Autores principales: | Smith, David P., Giles, Kevin, Bateman, Robert H., Radford, Sheena E., Ashcroft, Alison E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
ACS Publications
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706321/ https://www.ncbi.nlm.nih.gov/pubmed/17964800 http://dx.doi.org/10.1016/j.jasms.2007.09.017 |
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