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Intermediates: ubiquitous species on folding energy landscapes?

Although intermediates have long been recognised as fascinating species that form during the folding of large proteins, the role that intermediates play in the folding of small, single-domain proteins has been widely debated. Recent discoveries using new, sensitive methods of detection and studies c...

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Detalles Bibliográficos
Autores principales: Brockwell, David J, Radford, Sheena E
Formato: Texto
Lenguaje:English
Publicado: Elsevier Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706323/
https://www.ncbi.nlm.nih.gov/pubmed/17239580
http://dx.doi.org/10.1016/j.sbi.2007.01.003