Local lung responses following endobronchial elastase and lipopolysaccharide instillation in sheep

Chronic lipopolysaccharide (LPS) exposure may contribute to the pathogenesis of a number of lung diseases including COPD and emphysema. We sought to develop a large- animal model of emphysema using repeated LPS administration into sheep lung segments. An experimental protocol was designed to facilit...

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Detalles Bibliográficos
Autores principales: Collie, D David S, McLean, Nicola, Sallenave, Jean-Michel, Baker, Alison, Blundell, Richard, Milne, Elspeth, Rhind, Susan, Woodall, Chris
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2006
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706618/
https://www.ncbi.nlm.nih.gov/pubmed/18046896

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