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Effects of cIAP-1, cIAP-2 and XIAP triple knockdown on prostate cancer cell susceptibility to apoptosis, cell survival and proliferation

BACKGROUND: Manipulating apoptotic resistance represents an important strategy for the treatment of hormone refractory prostate cancer. We hypothesised that the Inhibitor of Apoptosis (IAP) Proteins may be mediating this resistance and knockdown of cIAP-1, cIAP-2 and XIAP would increase sensitivity...

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Detalles Bibliográficos
Autores principales:	Gill, Catherine, Dowling, Catherine, O'Neill, Amanda J, Watson, R William G
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706796/ https://www.ncbi.nlm.nih.gov/pubmed/19549337 http://dx.doi.org/10.1186/1476-4598-8-39

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