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Generation and characterization of human insulin-releasing cell lines

BACKGROUND: The in vitro culture of insulinomas provides an attractive tool to study cell proliferation and insulin synthesis and secretion. However, only a few human beta cell lines have been described, with long-term passage resulting in loss of insulin secretion. Therefore, we set out to establis...

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Detalles Bibliográficos
Autores principales: Labriola, Leticia, Peters, Maria G, Krogh, Karin, Stigliano, Iván, Terra, Letícia F, Buchanan, Cecilia, Machado, Marcel CC, Joffé, Elisa Bal de Kier, Puricelli, Lydia, Sogayar, Mari C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706802/
https://www.ncbi.nlm.nih.gov/pubmed/19545371
http://dx.doi.org/10.1186/1471-2121-10-49